Review





Similar Products

mouse cortical neuronal cultures  (Thermo Fisher)
90
Thermo Fisher mouse cortical neuronal cultures
(A) Schematic connecting <t>neuronal</t> activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in <t>mouse</t> primary <t>cortical</t> neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.
Mouse Cortical Neuronal Cultures, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+cortical+neuronal+cultures/mouse+cortical+neuronal+cultures/pmc10802743-84-0-7
Average 90 stars, based on 1 article reviews
mouse cortical neuronal cultures - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
489 mouse primary neurons 490 primary cortical neuronal cultures  (Janvier Labs)
86
Janvier Labs 489 mouse primary neurons 490 primary cortical neuronal cultures
(A) Schematic connecting <t>neuronal</t> activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in <t>mouse</t> primary <t>cortical</t> neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.
489 Mouse Primary Neurons 490 Primary Cortical Neuronal Cultures, supplied by Janvier Labs, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+cortical+neuronal+cultures/cortical+networks+networks+neuronal+neuronal+primary+rat/10__1016_slash_j__omta__2025__201658-195-0-20
Average 86 stars, based on 1 article reviews
489 mouse primary neurons 490 primary cortical neuronal cultures - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
mouse primary cortical neuron cultures  (Charles River Laboratories)
86
Charles River Laboratories mouse primary cortical neuron cultures
(A) Schematic connecting <t>neuronal</t> activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in <t>mouse</t> primary <t>cortical</t> neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.
Mouse Primary Cortical Neuron Cultures, supplied by Charles River Laboratories, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+cortical+neuronal+cultures/cortical+neurons+primary/pmc11126784-593-0-10
Average 86 stars, based on 1 article reviews
mouse primary cortical neuron cultures - by Bioz Stars, 2026-09
86/100 stars
  Buy from Supplier
primary mouse cortical neuron cultures  (Creative Biolabs)
90
Creative Biolabs primary mouse cortical neuron cultures
(A) Schematic connecting <t>neuronal</t> activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in <t>mouse</t> primary <t>cortical</t> neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.
Primary Mouse Cortical Neuron Cultures, supplied by Creative Biolabs, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+cortical+neuronal+cultures/primary+mouse+cortical+neuron+cultures/10__61373_slash_gp024r__0043-70-5-13
Average 90 stars, based on 1 article reviews
primary mouse cortical neuron cultures - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier
primary mouse cortical neuron culture  (Thermo Fisher)
90
Thermo Fisher primary mouse cortical neuron culture
(A) Schematic connecting <t>neuronal</t> activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in <t>mouse</t> primary <t>cortical</t> neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.
Primary Mouse Cortical Neuron Culture, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mouse+cortical+neuronal+cultures/primary+mouse+cortical+neurons/pm36001963-198-0-14
Average 90 stars, based on 1 article reviews
primary mouse cortical neuron culture - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


(A) Schematic connecting neuronal activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in mouse primary cortical neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.

Journal: Research Square

Article Title: Regulation of neuronal circHomer1 biogenesis by PKA/CREB/ERK-mediated pathways and effects of glutamate and dopamine receptor blockade

doi: 10.21203/rs.3.rs-3547375/v1

Figure Lengend Snippet: (A) Schematic connecting neuronal activity and CREB-mediated Eif4a3/Fus mRNA transcription for the subsequent circHomer1 biogenesis. (B-D) Relative to vehicle, circHomer1, Eif4a3 and Fus mRNA levels (quantifications were based on qRT-PCR and normalized to 18S rRNA) after treatment with CREB inhibitor (B-C) in two rounds of experiment at (B) dose < IC50 and (C) dose equal to IC50 in mouse primary cortical neurons (treatment was done for 24hours) and (D) after treatment with a CREB-CBP inhibitor at a dose equal to IC50. Mean ± SEM. ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, based on two tailed one sample t-test relative to vehicle. For circHomer1 after treatment with < IC50 dose (B): t = 3.106, df = 2, and p = 0.0899. For Eif4a3 mRNA after treatment with < IC50 dose (B): t = 3.441, df = 3, and p = 0.0412. For Fus mRNA after treatment with < IC50 dose (B): t = 10.53, df = 2, and p = 0.0089. For circHomer1 after treatment with = IC50 dose (C): t = 12.53, df = 4, and p = 0.0002. For Eif4a3 mRNA after treatment with = IC50 dose (C): t = 7.358, df = 4, and p = 0.0018. For Fus mRNA after treatment with = IC50 dose (C): t = 20.86, df = 4, and p < 0.0001. For circHomer1 after treatment with CREB-CBP inhibitor (D): t = 10.29, df = 4, and p = 0.0005. For Eif4a3 mRNA after treatment with CREB-CBP inhibitor (D): t = 8.238, df = 5, and p = 0.0004. For Fus mRNA after treatment with CREB-CBP inhibitor (D): t = 15.60, df = 5, and p < 0.0001. In all bar graphs the individual replicates are shown within the graph.

Article Snippet: Mouse cortical neuronal cultures were purchased from ThermoFisher Scientific – Catalog number: A15585 (C57BL/6 mice).

Techniques: Activity Assay, Quantitative RT-PCR, Two Tailed Test